Hyperoxia is a significant increase in the availability of oxygen in the blood plasma. It promotes cellular metabolism and allows oxygen to reach the brain, cartilage, bones, and tissues that, due to various circulatory disorders, do not receive it properly.  

Mechanism of action of HBOT

The patient breathes high doses of 02 in a hyperbaric environment.
High HYPEROXIA increases the volume of dissolved oxygen in the blood plasma.
The greatest diffusion of oxygen reaches the less irrigated tissues.
Hyperoxia produces a wide variety of physiological benefits to the body.

Physiological effects

The hyperbaric chamber produces strong hyperoxia that generates different benefits for the organism.
Repair of peripheral neuronal fibres
Oxygen promotes plasticity of the nervous system.
Hyperoxia supports the formation of small blood vessels, and promotes perfusion.
Stimulation of collagen synthesis
Hyperoxia induces the hydroxylation of proline and the proliferation of fibroblasts. It favors the collagen synthesis, that is fundamental for the wound healing process.
Bactericidal activity
Hyperoxia generates reactive oxygen species that increase the activity of antibiotics and act against bacterial biofilm.
Regulation of oxidative stress and the inflammatory response
Hyperoxia acts on regulators and mediators of the inflammatory response and decreases oxidative stress, so it has anti-inflammatory effects and decreases cellular damage.
Increases cerebral blood flow and neuroprotection
Improves perfusion thanks to the formation of new vessels and cerebral oxygenation decreases edema and inflammation of the central nervous system.
Hyperoxia promotes the differentiation of bone-forming cells and promotes osteogenesis and bone repair.
Reduction of ischemia-reperfusion damage
Improves tissue microcirculation, decreases the production of reactive oxygen species, and increases their degradation through stimulation in the expression of antioxidant enzymes.
Analgesic effect
It has an analgesic effect in pathologies with nociceptive and neuropathic components, through tissue repair, recovery of function, and decrease of inflammation.

Hyperbaric Medicine History

1662 - Great Britain

Development of the first hyperbaric chamber sketch called “Domicillium”.

1775 - 1789

Discovery of oxygen properties.

1860 - Canada

Construction of the first hyperbaric chamber.


Treatment of diver decompressive disease.

1920-1930- EEUU

Treatment for "hypoxic" problems (circulatory, cardiac). 

Construction of the "Spherical Cunningham-Timken section-text", a 5-floor hyperbaric chamber.

1959 - Amsterdan

First hyperbaric operating room for cardiopulmonary surgeries and skin grafts. 

1960 - USA and rest of the world

First successful treatment of gas gangrene.

The indications for injuries, anaerobic infections and carbon monoxide poisoning are extended.

1974-1990 - Russia

The emergency of the hyperbaric medicine centers in Moscow.

News - USA and Israel

Pressures lower than 2 ATA are described as optimal for neurological disorders and the indications are significantly expanded.


Safe, efficient and easy to operate


Safe, efficient and easy to operate

*These statements have not been evaluated by the US Food and Drug Administration.